Muscle Action, Trace Elements and Related Nutrients: The Myothermogram
In: Chazot G, Abdulla M, Arnaud P, eds. Current Trends in Trace Element Research: Proceedings of International Symposium on Trace Elements. Paris, 1987, Smith-Gordon, London, 1989, pp79-85
In the investigation of muscle problems it is relatively easy to measure the circulating levels of nutrients known to be involved in muscle function. Such data frequently fail to provide enough information about metabolic problems within the muscle. In diagnosis and in following the treatment of muscle-related problems a functional test is needed.
In the subcellular events responsible for muscle contraction the biochemical energy utilized must equal the energy output of the system and this is essentially the external work done plus the heat energy produced. The external work can be limited so that a plot of the heat produced during contraction and relaxation should reflect the subcellular chemistry. The limiting factors are the difficulty of detecting very small temperature changes and the efficient way in which muscle heat is conducted away by the circulation.
The use of sensitive temperature recording equipment in a clinical test of muscle action is described. Abnormalities of potential diagnostic significance are demonstrated in deficiencies of magnesium, calcium, iron (in children), manganese and folate. The test also detects reduced oxygenation or perfusion and abnormal results are seen in thyroid disorders. It will be shown that muscle damage can result from exercise during magnesium deficiency.
NOTICE : Biolab Limited has gone into administration
14th July 2022
Biolab Limited has gone into administration due to the delay by The Care Quality Commission in processing our application to transfer our business activities to our laboratory site in West London following an earlier temporary suspension.
We always remained highly confident that Biolab would reopen and invested heavily in relocating the business, retaining and retraining our employees, developing new and improved methods of work and updating our documentation, so this comes as a huge disappointment for us all, but as you’ll appreciate no business can continue indefinitely without an income.
We are no longer able to process any samples for testing.
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