Investigation for Fermentation in the Small Intestine
The
Gut Fermentation Test (GFT)
Principle:
Yeast cells in the gut ferment glucose to alcohol, which then passes into the blood stream. This test follows the changes in blood alcohol concentrations following a glucose challenge.
Glucose is normally absorbed rapidly, including some absorption from the stomach. A method is therefore required that ensures an adequate amount of glucose from a glucose load passes into the duodenum. In this test, glucose encased in hardened gelatin capsules is used. Disintegration of these capsules in the stomach is much less likely to occur if taken in conjunction with a 5% glucose solution.
Patient Preparation:
1. No alcohol for at least 24 hours prior to the test.
2. Patient should fast
for at least 3 hours prior to the test.
Test Protocol:
1. The patient is given 1g glucose in hardened gelatine capsules (2 x 500mg capsules) along with 4g glucose dissolved in 80-100ml water.
2. Take a 2ml blood sample into a fluoride/oxalate tube after 60 minutes [Note: Do not use an alcohol swab as this may affect the test results]..
3. Send the blood sample to Biolab at the above address. You may use the sample carrier provided in the kit.
If you have any queries
regarding this test please contact the laboratory.
For further details please contact Biolab info@biolab.co.uk